Lucius Cary talks about investing in technology start-ups


Oxford Technology Management has specialised in making investments in start-up technology companies in and around Oxford since 1983. In total, more than 150 investments have been made through 12 different funds. The latest of these is the Oxford Technology Seed Enterprise Investment Scheme and Enterprise Investment Scheme Combined Fund – OT(S)EIS. This fund made its first investment in 2012 and by 31 Dec 2016, had made 50 investments in 23 companies.


Investing in technology start-ups is one of the highest risk of all forms of investment. There are so many things which can and do go wrong – the technology may not work, the market may not develop as expected, others may come up with even better technology etc. But the other side of the coin is that the returns can be exceptionally large when things go well. The new SEIS scheme is ideally suited to this type of investment, since investors get 50% of their investment back against income tax and if the investment fails – there are further tax refunds, so the losses are greatly reduced on the failures. If the investments go well, then all the gains are tax free. SEIS investments are also good for Inheritance Tax planning, because they guarantee that after two years shares may be passed to heirs and are free of IHT.

The reason for making investments only in and around Oxford is that we become actively involved with our investees. We all have backgrounds in science and engineering and aim to understand the technology, and we have also been involved in starting and growing many businesses before. Those in whom we invest may be Nobel Laureate scientists, but they will probably not have filled in a VAT return before or negotiated a deal with a distributor in the US. Our style is to have frequent short management meetings, rather than long monthly or quarterly board meetings. And we often accompany the founders/MDs to key meetings with customers/suppliers/distributors etc.

The table below shows our portfolio of investments thus far. For each investee, the gross amount invested is shown the net cost of investment after tax refunds and the fair value of the investment. We calculate the fair value by using the latest share price at which money has been invested in each company. If no money has been invested since the original investment, we either write the value of the investment down if it is falling behind the original business plan or we keep it at the price of the original investment.  So to this extent, the valuations are conservative.



The overall figures, as at 31 December 2016 are as follows:


Total cost of investments     £3.0m

Net cost of investments         £1.8m

Fair value                                  £4.8m

Capital Gain                              £3.0m  (on paper only)


Of course past performance is no guide to future performance, but we believe that investing in high-risk, high-reward investments through the SEIS scheme, and then having the capacity to follow on with EIS investments makes economic sense and should continue to produce good returns. It is also interesting.

NB: The quarterly report contains a page of information on each investment, including the two which have failed, and may be downloaded from

Almost by definition, technology can be sold globally. An example that can illustrate this is Combat Medical, in which we were the first external investor. The company has developed a better treatment for bladder cancer – instead of surgery, which is expensive and painful, a warm chemotherapy liquid is circulated through the bladder. It is painless and may be administered by a nurse in an hour. More than 15,000 treatments have been carried out and it is now in use in 30 countries (mainly in Spain and the UK thus far). However, bladder cancer is a big problem in China too – a country where it is relatively difficult to make sales. As a response, we started Oxford Technology China in January 2017, in a collaboration with Chenjie Ma, who graduated from Oxford in Engineering in 2014, then worked with us in the UK and has now gone to China. Her role is to help companies such as Combat to find Chinese investors and to make sales in China, by whatever means is most suited for the particular company.



You might also like More from author